4 Topic Commentaries

The Missing Pieces of the Marmoset Genome

The Missing Pieces of the Marmoset Genome

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  Prajna Hebbar, Ph.D. student

  Genomics

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  UC Santa Cruz Genomics Institute, University of California, Santa Cruz

  Routine T2T genomics is making findings easier and more plausible, as we’re able to much more easily access these complex regions. It’s great to be in an era where we’re not stuck with the technical problems—we can go into the biology and make discoveries relevant to human health.

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  Benedict Paten, Ph.D.

  Computational genomics

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  UC Santa Cruz Genomics Institute, University of California, Santa Cruz

  We also identified sex differences in the distribution of these genes, a pattern that has previously been reported in orangutans and gibbons, widening our understanding of these genes that are extremely important to the biosynthesis of cells. While these sex differences may not have an effect on the species, now that we can do T2T sequences, we’ll find out more.

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  Jeffrey Rogers, Ph.D.

  Primate genomics

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  Baylor College of Medicine

  Researchers may have been more reluctant to study the marmoset due to lack of basic information, but this genome sequence opens new avenues for future research relevant to various aspects of human health and disease.

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  Richard A. Gibbs, Ph.D.

  Genomics

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  Baylor College of Medicine

  Each new non-human primate genome adds to a deeper understanding of human biology.

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