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The Pathologist / Issues / 2026 / September / COVID-19 May Reactivate Dormant Viruses
Biochemistry and molecular biology Infectious Disease Screening and monitoring Insights

COVID-19 May Reactivate Dormant Viruses

Nearly half of hospitalized patients had detectable reactivation of at least one chronic virus

09/07/2026 News 3 min read
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4 Topic Commentaries

COVID-19 May Reactivate Dormant Viruses

COVID-19 May Reactivate Dormant Viruses

  • Cole Maguire
    Cole Maguire, Medical Student (MS2); completed PhD research

    Neuroscience

    •

    Dell Medical School at The University of Texas at Austin

    This finding suggests that COVID-19 may not always act as a single viral infection and may disrupt the body’s internal ecosystem of dormant viruses, creating a state of ‘dysvirosis,’

    Source
  • Esther Melamed
    Esther Melamed, MD, PhD

    Neurology (Neuroimmunology)

    •

    Dell Medical School at The University of Texas at Austin

    The next step is determining whether identifying and treating reactivated viruses can improve outcomes for patients with acute COVID-19 and long COVID.

    Source
  • Kristen Pogreba-Brown
    Kristen Pogreba-Brown, PhD, MPH

    Epidemiology

    •

    The University of Arizona Health Sciences

    One of several theories about long COVID is that an acute infection leads to an activation of dormant viruses, such as the Epstein-Barr virus,

    Source
  • Michael Peluso
    Michael Peluso, MD

    Infectious Diseases

    •

    University of California, San Francisco

    We’ve also been interested in the relationship between long COVID and prior Epstein-Barr infection, because people with reactivation of that infection appear twice as likely to report having long COVID.

    Source

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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