3 Topic Commentaries

Urinary Markers Show Promise in ASD

Urinary Markers Show Promise in ASD

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  Christina K. Flynn, PhD

  Chemical engineering; microbiome-derived urinary biomarkers and diagnostics in ASD

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  Arizona State University — Biodesign Center for Health Through Microbiomes

  What we've discovered is that 80 to 90% of children with autism have extremely high levels of one or more microbially derived metabolites. Using this test will tell you which young children are at high risk for being diagnosed with autism, and guide treatment in those who have already been diagnosed to help them lead their best lives.

  Source
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  James B. Adams, PhD

  Chemical/materials engineering; autism biomedical and microbiome-metabolite research

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  Arizona State University

  What’s really striking about the bacteria is that they make metabolites that are basically altered versions of serotonin and dopamine. These are two key neurotransmitters that affect mood, cognition and memory. This could explain many of the symptoms and co-occurring symptoms in children with autism — their social communication, anxiety, depression and attention.

  Source
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  Rosa Krajmalnik-Brown, PhD

  Environmental engineering; human gut microbiome and ASD

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  Arizona State University

  I am excited about the MDM test, which includes important microbial metabolites, previously hypothesized to be linked with autism. This test can be a great way to assess this important microbial contribution.

  Source