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The Pathologist / Issues / 2026 / June / Doing More With Every Biopsy
Oncology Biochemistry and molecular biology Endocrinology Microscopy and imaging Digital Pathology Molecular Pathology

Doing More With Every Biopsy

Virtual staining aims to support pathology workflows by preserving tissue for downstream molecular and spatial analyses

By Jessica Allerton 06/26/2026 Discussion 4 min read
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4 Topic Commentaries

Doing More With Every Biopsy

Doing More With Every Biopsy

  • Jillian Phallen
    Jillian Phallen, PhD

    Cancer genomics; liquid biopsy/ctDNA

    •

    Johns Hopkins Kimmel Cancer Center

    Noninvasive liquid biopsies identifying tumor-specific changes provide an opportunity for widespread implementation of monitoring approaches for different cancer types in a variety of clinical settings.

    Source
  • Pedram Razavi
    Pedram Razavi, MD, PhD

    Breast medical oncology; molecular oncology

    •

    Memorial Sloan Kettering Cancer Center

    Liquid biopsy can provide a more global picture of tumor mutations as all the tumor sites potentially contribute to the cfDNA pool in circulation.

    Source
  • George Vasmatzis
    George Vasmatzis, PhD

    Molecular pathology; biomarker discovery

    •

    Mayo Clinic

    With liquid biopsies, we don’t have to wait for tumor growth to get a DNA sample. This important discovery makes it possible for us to detect recurrence of the disease earlier than other diagnostic methods. We can repeat liquid biopsies to monitor the progression of the cancer. That gives hope of a better treatment plan over time.

    Source
  • Lisa Rimsza
    Lisa Rimsza, MD

    Hematopathology; lymphoma diagnostics

    •

    Mayo Clinic

    We specialize in developing new tests to make sure we can get the most accurate diagnosis for the patient, and also figure out whether their disease is likely to be more or less aggressive.

    Source

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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About the Author(s)

Jessica Allerton

Deputy Editor, The Pathologist

More Articles by Jessica Allerton

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