Objective:

To analyze the oral microbial composition of historical Japanese populations through dental calculus and compare it with modern samples.

Approach:

Key Findings:

• 285 oral microbial species were identified, showing clear differences between ancient and modern oral microbiomes.
• Increased prevalence of Methanobrevibacter oralis, associated with periodontitis, was found in historical samples.
• Regional variations were noted between mainland Japan and Okinawa in the prevalence of specific microbial taxa.
• Distinct microbial lineages were associated with different historical periods, indicating demographic and lifestyle influences on oral microbial evolution.
• Two major historical clades of M. oralis were identified, with clade membership linked to host sex and practices like ohaguro.

Interpretation:

Conclusion:

Sources:

• Scientific Reports
Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.