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The Pathologist / Issues / 2026 / January / Is PointofCare Hepatitis C Virus Testing Too Expensive
Microbiology & Immunology Liquid biopsy Point of care testing Omics Screening and monitoring Molecular Pathology Research and Innovations

Is Point-of-Care Hepatitis C Virus Testing Too Expensive?

RNA testing carries substantial cost burden for hospitals, study finds

01/14/2026 News 2 min read
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Clinical Scorecard: Is Point-of-Care Hepatitis C Virus Testing Too Expensive?

At a Glance

CategoryDetail
ConditionHepatitis C Virus (HCV)
Key MechanismsPoint-of-care RNA testing vs. traditional two-step testing
Target PopulationSafety-net populations in emergency departments
Care SettingEmergency departments and outpatient clinics

Key Highlights

  • Point-of-care RNA testing could increase hospital laboratory costs by up to 260%.
  • Emergency department testing increased 682% from 2017 to 2024.
  • HCV antigen testing is a cost-effective alternative, adding only $11,494 in annual costs.

Guideline-Based Recommendations

Diagnosis

  • Consider point-of-care RNA testing for immediate treatment initiation.

Management

  • Evaluate cost implications of point-of-care testing versus traditional methods.

Monitoring & Follow-up

  • Track antibody positivity rates in different care settings.

Risks

  • Increased laboratory costs may impact other testing services.

Patient & Prescribing Data

Patients diagnosed with HCV in emergency departments.

Immediate treatment initiation is possible with rapid RNA tests.

Clinical Best Practices

  • Implement targeted deployment strategies for HCV testing.
  • Consider HCV antigen testing as a cost-effective alternative.

References

  • Journal of Clinical Microbiology

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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