5 Key Takeaways

• 1

  RNACOREX is a computational tool that identifies disease-associated RNA regulatory networks for classifying patient samples based on gene expression data.

• 2

  The software focuses on interactions between microRNAs and messenger RNAs, which are crucial for gene regulation but challenging to interpret.

• 3

  RNACOREX filters miRNA–mRNA interactions using established databases and scores them based on structural and functional relevance to clinical outcomes.

• 4

  The tool builds probabilistic models to analyze RNA expression values, generating predictions and an interpretable network of RNA interactions.

• 5

  RNACOREX achieved classification performance comparable to machine learning methods and provides visual representations of regulatory networks.