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Study published in the Journal of Clinical Pathology.
Investigated p21 and EGFR roles in CRC.
Analyzed 12,319 CRC patients from 2008-2020.
High p21 linked to longer survival; high EGFR linked to shorter survival.
Used immunohistochemistry for biomarker quantification.
Notable correlations found with tumor characteristics.
Multivariate analysis identified significant prognostic factors.
