Clinical Scorecard: Building Consistency into NGS Workflows for Cancer Sample Profiling and More

At a Glance

Key Highlights

• 15 minutes of hands-on time required
• Compatible with SureSelect Cancer assays
• Generates sequencing-ready libraries for various applications
• Supports input as low as 10 ng DNA or RNA
• Ensures reproducibility and consistency in workflows

Guideline-Based Recommendations

Diagnosis

• Utilize NGS for comprehensive genomic profiling of cancer samples

Management

• Implement automated workflows to enhance efficiency in library preparation

Monitoring & Follow-up

• Incorporate integrated QC steps to ensure consistency in results

Risks

• Potential variability in results without proper QC measures

Patient & Prescribing Data

Cancer patients undergoing genomic profiling

Targeted NGS library preparation facilitates detection of somatic variants

Clinical Best Practices

• Adopt automated systems for NGS workflows to reduce hands-on time
• Ensure compatibility with established cancer assays for accurate profiling
• Regularly validate QC processes to maintain workflow consistency

References