Objective:

To present a new portable analyzer for detecting anti-avian influenza antibodies in blood serum.

Approach:

• Technology Description: The analyzer utilizes liquid crystal molecules, an image sensor, and a microfluidic device to indicate antibody presence within 20 minutes.
• Testing Procedure: Serum and a fluorescein-labeled protein reagent are mixed for 15 minutes before being injected into the microfluidic device for measurement.

Key Findings:

• The analyzer weighs 5.5 kg and provides rapid results.
• The fluorescein-labeled protein reagent specifically binds to the anti-H5 avian influenza antibody.
• The test measures polarization changes due to molecular movements of bound antibodies.

Interpretation:

Conclusion:

The portable analyzer offers a quick method for detecting avian influenza antibodies and shows potential for broader applications.

Sources:

• Hokkaido University