Histology Histology Training and education

Case of the Month

12/02/2019 Quick Read (pre 2022) 1 min read

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Objective:

To present a clinical case involving a right parotid mass and solicit a diagnosis.

Approach:

Case Presentation: A 45-year-old female presented with a right parotid mass which was completely excised.
Diagnosis Options: The possible diagnoses included pleomorphic adenoma, salivary duct carcinoma, chronic sclerosing sialadenitis, and sclerosing polycystic adenosis.

Key Findings:

The answer to the previous month's case was a fibroepithelial polyp (FEP).
FEPs are rare, benign, mesenchymal lesions commonly found in the ureters and renal pelvis.
Approximately 70% of patients with FEPs are males, with a mean age of 40 years.
Common symptoms include flank pain and hematuria.
The prognosis for patients with FEPs is excellent.

Interpretation:

Limitations:

The etiology of FEPs is uncertain.
Differential diagnosis includes urothelial papilloma, inflammatory polyps, inverted papilloma, and florid cystitis cystica/glandularis.

Conclusion:

Sources:

The Pathologist

References

TR Williams et al., “Fibroepithelial polyps of the urinary tract”, Abdom Imaging, 27, 217 (2002). PMID: 11847584.
T Tsuzuki, JI Epstein, “Fibroepithelial polyp of the lower urinary tract in adults”, Am J Surg Pathol, 29, 460 (2005). PMID: 15767798.
HJ Kiel et al., “Benign ureteral tumors: Four case reports and a review of the literature”, Urol Int, 63, 201 (1999). PMID: 10738195.
I Karaca I, Şencan A, Mir E, Sayan A, Ortac R. “Ureteral fibroepithelial polyps in children”, Pediatr Surg Int, 12, 603 (1997). PMID: 9354735.
RH Young, “Fibroepithelial polyp of the bladder with atypical stromal cells”, Arch Pathol Lab Med, 110, 241 (1986). PMID: 3753860.
W Geng et al., “The diagnosis and differential diagnosis of ureteral fibroepithelial polyps”, Cancer Biology & Medicine, 3, 373 (2006).