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The Pathologist / Issues / 2025 / September / Should Grade Group 1 Be Called Cancer / Summary
Oncology Clinical care Screening and monitoring

Should Grade Group 1 Be Called Cancer?

A large population-based study raises questions about diagnosis, terminology, and counseling for patients with low-grade prostate cancer

By Jessica Allerton 09/25/2025 Discussion 2 min read
article Full Article Summary Notecard

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A debate is emerging regarding the designation of Grade Group 1 (GG1) prostate cancer, with concerns that grading may overlook vital diagnostic indicators, such as PSA levels. Research from Weill Cornell Medicine reveals that 1 in 6 men diagnosed with GG1 are later determined to have intermediate or high-risk disease, raising issues about patient understanding. Bashir Al Hussein emphasizes the need for better risk stratification combining histopathology, imaging, and clinical features to guide management decisions, ensuring patients receive accurate prognostic insights.

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About the Author(s)

Jessica Allerton

Deputy Editor, The Pathologist

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