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Shifts in Influenza Activity 2018 to 2023

Influenza trends and respiratory virus co-infections showed shifts in activity patterns and age-related risks during the COVID-19 pandemic years

09/29/2025 News 2 min read

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  1. Children under 5 have higher odds of influenza co-infection.

  2. Study analyzed 386,283 samples from 2018-

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  • Influenza positivity peaked in 2019 with 14.4 percent.

  • Co-infections occurred most with rhinovirus.

  • Influenza activity increased post-pandemic measures.

  • Multiplex PCR assays expanded testing volumes significantly.

  • Severe acute respiratory syndrome coronavirus 2 was detected in some cases.

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