Tumor Budding Signals Higher Liver Cancer Mortality Risk

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1. Over 500 cases of HCC studied from 1986-2022.

2. Ten or more tumor buds linked to high mortality.

3. Tumor budding identified as an independent risk factor for disease-specific mortality.

4. 44.6 percent of surgically treated patients were bud-positive.

5. TSR showed no significant correlation with survival.

6. Detection sensitivity for tumor budding from biopsies was only 22 percent.