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The Pathologist / Issues / 2025 / October / Helicobacter Pylori Strongly Linked to Gastric Metaplasia / Notecards
Histology Clinical care Screening and monitoring

Helicobacter Pylori Strongly Linked to Gastric Metaplasia

Researchers found no progression to neoplasia among gastric intestinal metaplasia subtypes, while confirming strong associations with Helicobacter pylori infection.

By Kathryn Wighton 10/13/2025 News 2 min read
article Full Article Summary Notecard

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  1. Subtypes of gastric intestinal metaplasia (GIM) include complete, incomplete, and mixed.

  2. GIM is a precursor lesion in gastric carcinogenesis.

  3. Study reviewed 206 biopsy cases over 52.2 months.

  4. No cases developed gastric dysplasia or adenocarcinoma during follow-up.

  5. H. pylori was associated with all GIM subtypes.

  6. Majority of GIM cases were located in the antrum.

  7. No link was found between GIM and smoking or alcohol use.

  8. Borderline association observed with hypertension.

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About the Author(s)

Kathryn Wighton

Editor, Conexiant

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