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The Pathologist / Issues / 2025 / October / Cracking Prostate Cancer’s Code: What the STAMPEDE Trial Reveals / Notecards

Cracking Prostate Cancer’s Code: What the STAMPEDE Trial Reveals

Genomic classifiers offer pathologists a clearer picture of tumor aggressiveness and progression

10/24/2025 5 min read
article Full Article Summary Notecard

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  1. STAMPEDE trial is focused on advanced prostate cancer treatments.

  2. Over 12,000 participants have contributed to this research.

  3. Genomic risk scores significantly impact treatment outcomes.

  4. PTEN loss correlates with chemotherapy benefits.

  5. Transcriptomic testing enhances traditional pathology in treatment decisions.

  6. Integrated genomic data can refine patient management strategies.

  7. Future research will explore additional molecular pathways in prostate cancer.

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