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The Pathologist / Issues / 2025 / May / Case of the Month: May 2025
Histology Professional Development

Case of the Month

Can you identify an additional lesion found in the breast of a patient with invasive ductal carcinoma?

By Mohan Narasimhamurthy, Melinda Sanders 05/28/2025 Learning 2 min read

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Case history

A 59-year-old female presented with a recent diagnosis of high-grade invasive ductal carcinoma of the right breast. During treatment planning, imaging revealed two additional lesions in the ipsilateral breast, which were biopsied to rule out satellite carcinomas. One lesion was fibrocystic, including columnar cell changes without atypia.  

The following are the images from the second lesion.

Histology


What is your diagnosis?

a) Metaplastic carcinoma 

b) Leiomyosarcoma

c) Myofibroblastoma with atypical leiomyomatous features

d) Fibromatosis

e) Solitary fibrous tumor


Click here to register your guess and see the answer.

Do you have an interesting case that you would like us to feature? Email it to edit@thepathologist.com.


Submitted by Mohan Narasimhamurthy, Assistant Professor of Pathology, Microbiology, and Immunology, and Melinda Sanders, Professor, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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About the Author(s)

Mohan Narasimhamurthy

Assistant Professor of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

More Articles by Mohan Narasimhamurthy

Melinda Sanders

Professor, Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

More Articles by Melinda Sanders

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Dive deeper into the world of pathology. Explore the latest articles, case studies, expert insights, and groundbreaking research.

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